Pharmacokinetics and pharmacodynamics of verapamil following sublingual and oral administration to healthy volunteers.
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Pharmacokinetics and pharmacodynamics of acetylsalicylic acid after intravenous and oral administration to healthy volunteers
BACKGROUND The pharmacology of single doses of acetylsalicylic acid (ASA) administered intravenously (250 or 500 mg) or orally (100, 300, or 500 mg) was evaluated in a randomized, placebo-controlled, crossover study. METHODS Blood and urine samples were collected before and up to 24 hours after administration of ASA in 22 healthy volunteers. Pharmacokinetic parameters and measurements of plat...
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ژورنال
عنوان ژورنال: British Journal of Clinical Pharmacology
سال: 1992
ISSN: 0306-5251
DOI: 10.1111/j.1365-2125.1992.tb04091.x